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interesting readings on Alzheimer and P53 used as a diagnostic biomarker

  • Biogen’s Aducanumab might work for early stage Alzheiemer

  • Zetterberg H and Burnham SC
    "Blood-based molecular biomarkers for Alzheimer’s disease" Mol Brain 12.26 (2019)

  • Sabapathy, Kanaga, and David P. Lane.
    "Understanding p53 functions through p53 antibodies." Journal of molecular cell biology 11.4 (2019): 317-329.

  • Jembrek MJ, et al.
    "The interactions of p53 with tau and Aß as potential therapeutic targets for Alzheimer’s disease." Progress in neurobiology 168 (2018): 104-127.

  • Arce-Varas, Memo M, Uberti D, et al.
    "Comparison of extracellular and intracellular blood compartments highlights redox alterations in Alzheimer's and mild cognitive impairment patients." Current Alzheimer Research 14.1 (2017): 112-122.

  • Buizza L, Memo M, Uberti D, et al.
    "Conformational altered p53 affects neuronal function: relevance for the response to toxic insult and growth-associated protein 43 expression." Cell death & disease 4.2 (2013): e484.

  • Buizza L, Memo M, Uberti D, et al.
    "Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease." PLoS One 7.1 (2012): e29789.

  • Lanni C, Memo M, Uberti D, et al.
    "p53 at the crossroads between cancer and neurodegeneration." Free Radical Biology and Medicine 52.9 (2012): 1727-1733.

  • Lanni C, Memo M, Uberti D, et al.
    "Unfolded p53 in blood as a predictive signature signature of the transition from mild cognitive impairment to Alzheimer's disease." Journal of Alzheimer's Disease 20.1 (2010): 97-104.

  • Lanni C, Memo M, Uberti D, et al.
    "Conformationally altered p53: a novel Alzheimer's disease marker?." Molecular psychiatry 13.6 (2008): 641.

  • Uberti D, Memo M, et al.
    "Identification of a mutant-like conformation of p53 in fibroblasts from sporadic Alzheimer's disease patients." Neurobiology of aging 27.9 (2006): 1193-1201.

Blood-based diagnostics for early detection of Alzheimer’s Disease

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